Development of Adverse Outcome Pathway for PPARγ Antagonism Leading to Pulmonary Fibrosis and Chemical Selection for Its Validation: ToxCast Database and a Deep Learning Artificial Neural Network Model-Based Approach
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Full article: Collaborative efforts are needed among the scientific community to advance the adverse outcome pathway concept in areas of radiation risk assessment
Adverse outcome pathways: Application to enhance mechanistic understanding of neurotoxicity
Toxics, Free Full-Text
Full article: Collaborative efforts are needed among the scientific community to advance the adverse outcome pathway concept in areas of radiation risk assessment
Defining Molecular Initiating Events in the Adverse Outcome Pathway Framework for Risk Assessment
Toxics, Free Full-Text
DDAC induces inflammation and fibroproliferation in the lungs. Mice
Full article: Bringing together scientific disciplines for collaborative undertakings: a vision for advancing the adverse outcome pathway framework
Effects of Class Imbalance and Data Scarcity on the Performance of Binary Classification Machine Learning Models Developed Based on ToxCast/Tox21 Assay Data
Integration of Computational Toxicology, Toxicogenomics Data Mining, and Omics Techniques to Unveil Toxicity Pathways
PPARγ agonists inhibit TGF-β induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosis
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