GPC2-CAR T cells tuned for low antigen density mediate potent
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Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
Preclinical development of a chimeric antigen receptor T cell therapy targeting FGFR4 in rhabdomyosarcoma - ScienceDirect
D3-GPC2-PBD is potently cytotoxic to GPC2-expressing SCLCs (A)
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CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice - ScienceDirect
Mechanisms of Resistance and Treatment of Relapse after CAR T-cell Therapy for Large B-cell Lymphoma and Multiple Myeloma - Transplantation and Cellular Therapy, Official Publication of the American Society for Transplantation and
PDF) Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
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Frontiers Fine-tuning the antigen sensitivity of CAR T cells: emerging strategies and current challenges
Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
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GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
CAR-T Therapies in Solid Tumors: Opportunities and Challenges
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research
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