Identification of and Structural Insights into Hit Compounds
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Full article: New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents

Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97
Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery

High-resolution structural information of membrane-bound α-synuclein provides insight into the MoA of the anti-Parkinson drug UCB0599

Hit-to-lead in drug discovery

Hit to Lead (H2L) Process in Drug Discovery
Advances in Ultrahigh Throughput Hit Discovery with Tandem Mass Spectrometry Encoded Libraries

CDoT Drug Discovery Project Capabilities

Hit Identification (Hit ID)

Predicting compound activity from phenotypic profiles and chemical structures

Structure based virtual screening: Fast and slow - Varela‐Rial - 2022 - WIREs Computational Molecular Science - Wiley Online Library
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